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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Glioma causes

Introduction

Overview

Overview

Common causes of glioma include genetic mutations (ERCC1, ERCC2, XRCC1, MGMT, IDH1, IDH2, p53, EGFR, TSC1, TSC2, RB1, APC, hMLH1, hMSH2, PMS2, PTEN, NF1, and NF2).^[1]^[2]

Causes

Causes

Common causes of glioma include genetic mutations.
The various genes include:^[1]^[2]
- ERCC1
- ERCC2
- XRCC1
- MGMT
- IDH1
- IDH2
- p53
- EGFR
- TSC1
- TSC2
- RB1
- APC
- hMLH1
- hMSH2
- PMS2
- PTEN
- NF1
- NF2

References

References

↑ ^1.0 ^1.1 Pathology of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma
↑ ^2.0 ^2.1 Schwartzbaum JA, Fisher JL, Aldape KD, Wrensch M (2006). “Epidemiology and molecular pathology of glioma”. Nat Clin Pract Neurol. 2 (9): 494–503, quiz 1 p following 516. doi:10.1038/ncpneuro0289. PMID 16932614.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]