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Glioma causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Overview

Common causes of glioma include genetic mutations (ERCC1, ERCC2, XRCC1, MGMT, IDH1, IDH2, p53, EGFR, TSC1, TSC2, RB1, APC, hMLH1, hMSH2, PMS2, PTEN, NF1, and NF2).^[1]^[2]

Causes

Causes

Common causes of glioma include genetic mutations.
The various genes include:^[1]^[2]
- ERCC1
- ERCC2
- XRCC1
- MGMT
- IDH1
- IDH2
- p53
- EGFR
- TSC1
- TSC2
- RB1
- APC
- hMLH1
- hMSH2
- PMS2
- PTEN
- NF1
- NF2

References

References

↑ ^1.0 ^1.1 Pathology of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma
↑ ^2.0 ^2.1 Schwartzbaum JA, Fisher JL, Aldape KD, Wrensch M (2006). “Epidemiology and molecular pathology of glioma”. Nat Clin Pract Neurol. 2 (9): 494–503, quiz 1 p following 516. doi:10.1038/ncpneuro0289. PMID 16932614.

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