
Health Dictionary
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Gliomatosis cerebri other imaging findings
Introduction
Overview
Overview
Other imaging studies for gliomatosis cerebri include MR spectroscopy (decreased N-Acetylaspartic acid (NAA)/creatine ratio and elevated choline/creatine ratio, choline/NAA ratio, and myoinositol), MR perfusion (low/normal relative cerebral blood flow), PET scan (markedly decreased accumulation of [18F]-fluorodeoxyglucose on F-18 FDG PET, hypermetabolism on C-11 methionine PET, and marked increase in cerebral blood flow on 15(O)-water PET), and bone scan (metastasis to bones).
Other Imaging Findings
Other Imaging Findings
Other imaging studies for gliomatosis cerebri include:[1][2][3]
1. Magnetic Resonance Spectroscopy
MR spectroscopy may be helpful in the diagnosis of gliomatosis cerebri. Findings on MR spectroscopy suggestive of gliomatosis cerebri include:[1][3]
- Decreased N-Acetylaspartic acid (NAA)/creatine ratio
- Elevated choline/creatine ratio
- Elevated choline/NAA ratio
- Elevated myoinositol
2. Magnetic Resonance Perfusion
MR perfusion may be helpful in the diagnosis of gliomatosis cerebri. Findings on MR perfusion suggestive of gliomatosis cerebri include:[1]
- βLow/normal relative cerebral blood flow (no vascular hyperplasia)
3. Positron Emission Tomography
PET scan may be helpful in the diagnosis of gliomatosis cerebri. Findings on PET scan suggestive of gliomatosis cerebri include:[1][2]
- F-18 FDG PET images show markedly decreased accumulation of [18F]-fluorodeoxyglucose (glucose hypometabolism).
- C-11 methionine PET images show hypermetabolism.
- 15(O)-water PET images show a marked increase in cerebral blood flow in gliomatosis cerebri lesions.
4. Bone Scan
References
References
- β 1.0 1.1 1.2 1.3 Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri
- β 2.0 2.1 Rajz GG, Nass D, Talianski E, Pfeffer R, Spiegelmann R, Cohen ZR (2012). “Presentation patterns and outcome of gliomatosis cerebri”. Oncol Lett. 3 (1): 209β213. doi:10.3892/ol.2011.445. PMCΒ 3362440. PMIDΒ 22740882.
- β 3.0 3.1 DesclΓ©e P, Rommel D, Hernalsteen D, Godfraind C, de Coene B, Cosnard G (2010). “Gliomatosis cerebri, imaging findings of 12 cases”. J Neuroradiol. 37 (3): 148β58. doi:10.1016/j.neurad.2009.12.001. PMIDΒ 20334921.
- β Beauchesne P (2011). “Extra-neural metastases of malignant gliomas: myth or reality?”. Cancers (Basel). 3 (1): 461β77. doi:10.3390/cancers3010461. PMCΒ 3756372. PMIDΒ 24212625.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
