Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Glomus tumor other diagnostic studies
Introduction
Overview
Overview
Other diagnostic studies for glomus tumor include immunohistochemistry staining, which demonstrates glomus cells positive for vimentin and alpha-smooth muscle actin and negative for desmin.[1]
Other Diagnostic Studies
Other Diagnostic Studies
- Other diagnostic studies for glomus tumor include immunohistochemistry staining, which demonstrates the following:[1][2]
- Other diagnostic studies for glomus tumors include clinical tests, such as:
- Love test[3][4]
- Orientative
- Probing with a needle or pointed instrument triggers pain in the affected area but not the area immediately adjacent to it
- Sensitivity= 100%
- Specificity= 0%
- Hildreth sign[3]
- Occurence of pain following induction of ischemia by application of a tourniquet to the glomus tumor mimicking median nail dystrophy (the longitudinal splitting in the midline of the nail)
- Highlights the vascular nature of the lesion
- Sensitivity= 77.4% – 92%
- Specificity= 91% – 100%
- Cold-sensitivity test[5]
- Application of cold water or ethanol to the affected area reproducing the symptoms
- Sensitivity= 100%
- Specificity= 100%
- Transillumination test[5][6]
- Performed in a darkened room by passing light through the finger pad
- An opaque red image is observed in the region of the tumor that allows estimation of its size
- Sensitivity= 23% – 38%
- Specificity= 90%
- Love test[3][4]
References
References
- ↑ 1.0 1.1 Kaye VM, Dehner LP (1991). “Cutaneous glomus tumor. A comparative immunohistochemical study with pseudoangiomatous intradermal melanocytic nevi”. Am J Dermatopathol. 13 (1): 2–6. PMID 1848411.
- ↑ Mravic M, LaChaud G, Nguyen A, Scott MA, Dry SM, James AW (2015). “Clinical and histopathological diagnosis of glomus tumor: an institutional experience of 138 cases”. Int J Surg Pathol. 23 (3): 181–8. doi:10.1177/1066896914567330. PMC 4498398. PMID 25614464.
- ↑ 3.0 3.1 Pater TJ, Marks RM (2004). “Glomus tumor of the hallux: case presentation and review of the literature”. Foot Ankle Int. 25 (6): 434–7. doi:10.1177/107110070402500614. PMID 15215032.
- ↑ Rohrich RJ, Hochstein LM, Millwee RH (1994). “Subungual glomus tumors: an algorithmic approach”. Ann Plast Surg. 33 (3): 300–4. PMID 7985967.
- ↑ 5.0 5.1 Kale SS, Rao VK, Bentz ML (2006). “Glomus tumor of the index finger”. J Craniofac Surg. 17 (4): 801–4. PMID 16877938.
- ↑ Ekin A, Ozkan M, Kabaklioglu T (1997). “Subungual glomus tumours: a different approach to diagnosis and treatment”. J Hand Surg Br. 22 (2): 228–9. PMID 9149994.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2] Roukoz A. Karam, M.D.[3]