Laboratory findings consistent with the diagnosis of glucagonoma include a serum glucagon concentration of 1000 pg/ml or greater.

The laboratory findings associated with glucagonoma are:^{[1][2][1][3][4]}

Serum glucagon

• Increased plasma glucagon levels >500 pg/mL (Normal glucagon level is less than 50 pg/mL).
• Concentrations above 1000 pg/mL are diagnostic of glucagonoma.
• Some conditions can increase glucagon level to a level less than 500 pg/mL such as fasting and hypoglycemia.
• Some symptomatic glucagonomas are associated with normal glucagon serum level. So, a serum glucagon concentration below 500 pg/mL does not exclude a glucagonoma.^[4]

Other laboratory findings

• Blood tests may also reveal low concentrations of amino acids, zinc, and essential fatty acids.
• A complete blood count (CBC) to diagnose anemia.