Glucagonoma physical examination
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2], Mohammed Abdelwahed M.D[3]
Overview
Overview
Common physical examination findings of glucagonoma include tachycardia, fever, rash, muscle atrophy. Cotton wool spots, flame hemorrhage, and dot-blot hemorrhages on fundoscopic examination of the eye may be present.
Physical Examination
Physical Examination
Common physical examination findings of glucagonoma include:
General Appearance
- Patients with glucagonoma are generally well-appearing
- Patient may appear thin and cachectic in advanced cases
Vital Signs
- Tachycardia may be present
- Fever may be present
Skin
- Erythematous, ring shaped rash that blisters, erodes, and crusts over suggesting necrolytic migratory erythema
HEENT
- Ophthalmoscopic exam may be abnormal with findings of cotton wool spots, flame hemorrhage, and dot and blot hemorrhage
Heart
- Tachycardia may be present
Extremities
- Muscle atrophy may be present
- Unilateral calf or thigh tenderness
- Unilateral calf or thigh swelling
- Unilateral calf or thigh warmth
- Unilateral calf or thigh erythema
- Palpable cord (a thickened palpable vein suggestive of thrombosed vein)
- Dilatation of unilateral collateral superficial veins
Neuromuscular
- Patient is oriented to persons, place, and time
- Hyporeflexia may be present
- Unilateral/bilateral sensory loss in the upper/lower extremity may be present
- Muscle atrophy may be present
- Vibration and joint position sense may be decreased
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