Glucose-6-phosphate dehydrogenase deficiency medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]

Overview

The mainstay of treatment for G6PD deficiency is avoidance of the foods such as fava beans and drugs that cause hemolysis. Pharmacologic medical therapy is recommended among patients with chronic hemolysis. Blood transfusion can be considered in the acute phase of hemolysis.

Medical Therapy

The mainstay of treatment for G6PD deficiency is avoidance of the foods such as fava beans and drugs that cause hemolysis.^[1]
Neonatal jaundice:
- Mild: no treatment
- Intermediate: phototherapy
- Severe: exchange transfusion
Blood transfusion in acute phase of hemolysis
Dialysis in acute kidney failure
Folic acid for patients with chronic hemolysis^[2]

Disease Name

Adult
- Folic acid: 1 mg daily

References

↑ Beutler E (December 1994). “G6PD deficiency”. Blood. 84 (11): 3613–36. PMID 7949118.
↑ Luzzatto L, Nannelli C, Notaro R (April 2016). “Glucose-6-Phosphate Dehydrogenase Deficiency”. Hematol. Oncol. Clin. North Am. 30 (2): 373–93. doi:10.1016/j.hoc.2015.11.006. PMID 27040960.

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[pmid7949118-1] Beutler E (December 1994). “G6PD deficiency”. Blood. 84 (11): 3613–36. PMID 7949118.

[pmid27040960-2] Luzzatto L, Nannelli C, Notaro R (April 2016). “Glucose-6-Phosphate Dehydrogenase Deficiency”. Hematol. Oncol. Clin. North Am. 30 (2): 373–93. doi:10.1016/j.hoc.2015.11.006. PMID 27040960.

[1]

[2]

Glucose-6-phosphate dehydrogenase deficiency medical therapy

Overview

Medical Therapy

Disease Name

References

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