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Granulomatosis with polyangiitis classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2];Associate Editor(s)-in-Chief: Amandeep Singh M.D.[3]Krzysztof Wierzbicki M.D. [4]

Overview

Overview

According to the American College of Rheumatology (ACR) Granulomatosis with polyangiitis is classified using 4 criteria.

Classification

Classification

According to the American College of Rheumatology (ACR) Granulomatosis with polyangiitis is classified by 4 criteria. They are:[1]

American College of Rheumatology (ACR) Classification of Granulomatosis with polyangiitis
Abnormal urinary sediment ( red cell casts or > 5 red blood cells per hpf)
Abnormal Chest radiography findings (nodules, cavities, or fixed infiltrates)
Nasal discharge or oral ulcers
Biopsy that presents with granulomatous inflammation

2 out of 4 criteria are needed to distinguish Granulomatosis with polyangiitis from other vasculitides, with a senstivity of 88% and senstivity of 92%.

References

References

  1. Leavitt RY, Fauci AS, Bloch DA, Michel BA, Hunder GG, Arend WP; et al. (1990). “The American College of Rheumatology 1990 criteria for the classification of Wegener’s granulomatosis”. Arthritis Rheum. 33 (8): 1101–7. PMID 2202308.

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