
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Group B streptococcal infection classification
Introduction
Overview
Overview
Group B streptococcal (GBS) infection can be classified into three main categories depending on the type of affected subjects. GBS infection can occur in pregnant women, neonates, or non-pregnant adults mainly the elderly.[1] Neonatal GBS infection can be further classified into early-onset or late-onset depending on the timing of the onset of the symptoms. Infections in newborns occurring within the first week of life are designated as early-onset disease, whereas late-onset infections occur in infants aged >1 week, with most infections evident during the first 3 months of life. [2]
Classification
Classification
Infection in Pregnant Women
GBS infection in pregnant women can lead to any of the following:
- No symptoms (asymptomatic carrier)
- Urinary tract infection
- Chorioamnionitis
- Endometritis
- Premature rupture of membrane
Infection in Neonates
GBS infection in neonates can be classified as:[2]
- Early onset infection (within 24-48 hours, up to one week after delivery), which can lead to any of the following:
- Late onset infection (after the first week, up to 3 months of life), which can lead to any of the following:
- Bacteremia without a focus of infection
- Sepsis
- Meningitis
- Pneumonia
- Focal infections (less commonly) such as adenitis, cellulitis, and arthritis[3]
Infection in Men and Non-Pregnant Women
GBS infection in non pregnant adults occurs mainly in elderly and subjects with underlying disease, such as diabetes.[1] GBS infection in elderly can manifest as any of the following:[4]
- Pneumonia
- Skin and soft tissue infection
- Osteomyelitis
- Septic arthritis
- Urosepsis
- Peritonitis
- Meningitis
- Endocarditis
- IV catheter infection
References
References
- ↑ 1.0 1.1 Edwards MS, Baker CJ (2005). “Group B streptococcal infections in elderly adults”. Clin Infect Dis. 41 (6): 839–47. doi:10.1086/432804. PMID 16107984.
- ↑ 2.0 2.1 Verani J.R., McGee L, and Schrag S.J. Prevention of Perinatal Group B Streptococcal Disease. Revised Guidelines from CDC, 2010.CDC.gov
- ↑ Berardi A, Rossi C, Lugli L, Creti R, Bacchi Reggiani ML, Lanari M; et al. (2013). “Group B streptococcus late-onset disease: 2003-2010”. Pediatrics. 131 (2): e361–8. doi:10.1542/peds.2012-1231. PMID 23296441.
- ↑ Farley MM (2001). “Group B streptococcal disease in nonpregnant adults”. Clin Infect Dis. 33 (4): 556–61. doi:10.1086/322696. PMID 11462195.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]
