Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
HIV associated nephropathy future or investigational therapies
Introduction
Overview
Overview
Therapies such as molecular targeting require more research.[1] Recently, there have been reports of successful kidney transplantation from HIV-positive donors to HIV-positive recipients.[2][3]
Future or Investigational Therapies
Future or Investigational Therapies
- Therapies such as molecular targeting for prevention or delaying the progression to end stage renal disease (ESRD) require more research. [1]
- Recently, there have been reports from USA and South Africa that have shown successful kidney transplantation from HIV-positive donors to HIV-positive recipients.[2][3]
- HIV superinfection and resistance to cART are among the most concerning risks in kidney transplantation in HIV-positive kidneys to HIV-positive recipients.[4]
- There is lack of data on the estimation of recurrent disease and long-term outcome is not clear.[1]
References
References
- ↑ 1.0 1.1 1.2 Menez S, Hanouneh M, McMahon BA, Fine DM, Atta MG (2018). “Pharmacotherapy and treatment options for HIV-associated nephropathy”. Expert Opin Pharmacother. 19 (1): 39–48. doi:10.1080/14656566.2017.1416099. PMC 6381591. PMID 29224373.
- ↑ 2.0 2.1 Muller E, Barday Z, Mendelson M, Kahn D (2015). “HIV-positive-to-HIV-positive kidney transplantation–results at 3 to 5 years”. N Engl J Med. 372 (7): 613–20. doi:10.1056/NEJMoa1408896. PMC 5090019. PMID 25671253.
- ↑ 3.0 3.1 Durand CM, Segev D, Sugarman J (2016). “Realizing HOPE: The Ethics of Organ Transplantation From HIV-Positive Donors”. Ann Intern Med. 165 (2): 138–42. doi:10.7326/M16-0560. PMC 4949150. PMID 27043422.
- ↑ Muller E, Barday Z (2018). “HIV-Positive Kidney Donor Selection for HIV-Positive Transplant Recipients”. J Am Soc Nephrol. 29 (4): 1090–1095. doi:10.1681/ASN.2017080853. PMC 5875954. PMID 29330339.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]