Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
HIV coinfection with hepatitis b laboratory findings
Introduction
Laboratory Findings
Laboratory Findings
Accurate assessment of HBV infection in HIV coinfected individuals is necessary in order to base therapeutic decisions. [1]
WHO advocates HBsAg testing especially in areas of high HBV prevalence; but additional testing for HBV markers such as HBeAg and HBV DNA and to assess stage of liver disease (e.g. liver enzymes, liver biopsy) may not be widely available in many resource limited countries.
Hoffman and Thio provided management recommendations for use in areas with limited resources. They recommend that HBsAg and liver enzymes be tested before ART, with liver enzymes being repeated once or twice during the first 3 months after commencing ART. Detection of HBV DNA is helpful but may not be available. Chronic HBV carriers with HBeAg positivity may benefit from starting anti-HBV therapy early. [2]
References
References
- ↑ Thio CL (2009). “Hepatitis B and human immunodeficiency virus coinfection”. Hepatology. 49 (5 Suppl): S138–45. doi:10.1002/hep.22883. PMID 19399813. Retrieved 2012-03-29. Unknown parameter
|month=ignored (help) - ↑ Hoffmann CJ, Thio CL (2007). “Clinical implications of HIV and hepatitis B coinfection in Asia and Africa”. Lancet Infect Dis. 7 (6): 402–9. doi:10.1016/S1473-3099(07)70135-4. PMID 17521593. Retrieved 2012-03-29. Unknown parameter
|month=ignored (help)
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]