Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
HLA-A11
Introduction
HLA-A11 (A11) is an HLA–A serotype. The serotype identifies the more common HLA-A*11 gene products. A11 is more common in eastern Asia particularly along the coastal regions of china.
Serotype
Serotype
| A*11 | A11 | A10 | Sample |
| allele | % | % | size (N) |
| *1101 | 99 | 2530 | |
| *1102 | 76 | 42 | |
| *1103 | 83 | 18 | |
| *1104 | 60 | 6 | |
| *1105 | 66 | 33 | 3 |
Serotyping of A11 demostrates better recognition of the *1101 gene products and poorer recognition of other A*11 gene products. Ther are ~40 recognized alleles of A*11. There is only one null classified as A11.
Disease Associations
Disease Associations
By allele
A*1104 is associated with increased risk for cervical neoplasia resulting from human papillomavirus infection[2]
A11-B Haplotypes
A11-B Haplotypes
A11-B13
- A11-Cw2-B13 (Li)
- A11-Cw9-B13 (Southern China & SE Asia)
- A11-C10-B13 Buyi
- A11-CBL-B13 Northern China
References
References
- ↑ derived from IMGT/HLA
- ↑ Chan D, Cheung T, Tam A, Cheung J, Yim S, Lo K, Siu N, Zhou D, Chan P (2005). “Risk association between human leukocyte antigen-A allele and high-risk human papillomavirus infection for cervical neoplasia in Chinese women”. J Infect Dis. 192 (10): 1749–56. PMID 16235173.