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HLA-B42

Introduction

HLA-B42 (B42) is an HLA–B serotype. The serotype identifies the HLA-B*4201 and *4202 gene products.[1] HLA-B*4201 is common Central Africa. (For terminology help see: HLA-serotype tutorial)

Serotype

Serotype

B42 serotype recognition of Some HLA B*42 allele-group gene products[2]
B*42 B42 other Sample
allele % % size (N)
4201 93 2 1015
4202 95 80

Serological typing for B*4201 and B*4202 is relatively efficient.


B*4201 allele frequencies

HLA B*4201 frequencies
freq
ref. Population (%)
[3] Zambia Lusaka 14.8
[3] Mali Bandiagara 13.8
[3] Burkina Faso Mossi 13.2
[3] South Africian Natal Zulu 12.0
[3] Burkina Faso Rimaibe 9.6
[3] South Africa Tswana 8.5
[3] Kenya Luo 7.7
[3] Kenya 7.3
[3] Kenya Nandi 6.9
[3] Zimbabwe Harare Shona 6.9
[3] Saudi Arabia 5.6
[3] Cameroon Yaounde 4.9
[3] Cameroon Beti 4.0
[3] Cameroon Bamileke 3.9
[3] Cameroon Sawa 3.8
[3] Ivory Coast Akan Adiopodoume 3.4
[3] Israel Gaza Palestinians 2.4
[3] India North Delhi 2.2
[3] Senegal Niokholo Mandenka 1.6
[3] Mbenzele Pygmy (C. Afr. Rep.) 1.5
[3] Iran Baloch 1.5
[3] Pakistan Baloch 1.5
[3] Sudanese 1.5
[3] Tunisia 1.5
[3] Pakistan Brahui 1.4
[3] Cameroon Bamileke 1.3
[3] Oman 1.3
[3] Sudanese 1.3
[3] Tunisia Tunis 1.1
[3] Zimbabwe Harare Shona 1.1
[3] Cameroon Bakola Pygmy 1.0
[3] Pakistan Pathan 1.0
[3] Portugal Centre 1.0
[3] Saudi Arabia Guraiat and Hail 1.0
[3] Morocco Casablanca 0.9
[3] Senegal Dakar 0.9
[3] Uganda Kampala 0.9
[3] Cape Verde Southeastern Islands 0.8
[3] Guinea Bissau 0.8
[3] United Arab Emerates 0.8
[3] Morocco Nador Metalsa Class I 0.7
[3] Pakistan Karachi Parsi 0.6
[3] Spain Majorca 0.6
[3] China Yunnan Han pop2 0.5
[3] England Newcastle 0.5
[3] Israel Arab Druse 0.5
[3] Israel Jews 0.5
[3] Italy Rome 0.5
[3] Guadalajara Mestizos (2) (Mexico) 0.5
[3] Morocco 0.5
[3] Pakistan Sindhi 0.5
[3] Senegal Niokholo Mandenka 0.5
[3] Singapore Riau Malay 0.5
References

References

  1. ↑ Marsh SG, Albert ED, Bodmer WF; et al. (2005). “Nomenclature for factors of the HLA system, 2004”. Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
  2. ↑ derived from IMGT/HLA
  3. ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 3.17 3.18 3.19 3.20 3.21 3.22 3.23 3.24 3.25 3.26 3.27 3.28 3.29 3.30 3.31 3.32 3.33 3.34 3.35 3.36 3.37 3.38 3.39 3.40 3.41 3.42 3.43 3.44 3.45 3.46 3.47 3.48 3.49 3.50 3.51 3.52 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). “New allele frequency database: http://www.allelefrequencies.net“. Tissue Antigens. 61 (5): 403–7. PMID 12753660. External link in |title= (help)

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