Developer site: The content shown here is test data.

MyEClinic
MyEClinic
Health Dictionary AI Health Chat Find an Online Doctor
A serene Zen garden with raked sand and smooth stones, symbolising clarity and calm

Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

Back to skin conditions

HLA-B59

Introduction


HLA-B59 (B59) is an HLA–B serotype. The serotype identifies the more common HLA-B*## gene products.[1] B59 is a hybrid between B*55 and B*51.[2] B59 is more common in Japan, Korea, N. China and Mongolia. (For terminology help see: HLA-serotype tutorial)

Serotype

Serotype

B59 serotype recognition of the HLA B*59 allele-group gene products[3]
B*59 B59 Other Sample
allele % % size (N)
5901 45 41 123
B*5901 allele frequencies

B*5901 allele frequencies

HLA B*5901 frequencies
freq
ref. Population (%)
[4] Okinawan (USA Hawaii) 6.3
[4] Japan (2) 2.7
[4] Tarialan Khoton (Mongolia) 2.4
[4] South Korea (3) 2.1
[4] Gipuscoa Basque (Spain) 2.0
[4] Japan Central 1.8
[4] Casablanca (Morocco) 1.8
[4] Hyogo (Japan) 1.6
[4] N. Korean (Harbin,China) 1.0
[4] Manchu (Harbin, China) 0.6
[4] Naxi (Yunnan, China) 0.6
[4] Girona (Catalonia,Spain) 0.6
[4] Algeria (1) 0.5
[4] Inner Mongolia (China) 0.5
[4] Khalkha (Mongolia) 0.5
[4] Shanghai (China) 0.3
[4] Essen (German ) 0.3
[4] Southern Han (China) 0.2
[4] Shij. Tian. (Beijing, China) 0.1
[4] Hakka (Taiwan) 0.1
Regions of higher B*5901 frequency
Japan
Korea
Mongolia
Heilongjiang
prov., China
(Harbin city)
References

References

  1. ↑ Marsh SG, Albert ED, Bodmer WF; et al. (2005). “Nomenclature for factors of the HLA system, 2004”. Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
  2. ↑ Hildebrand WH, Domena JD, Parham P (1993). “Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8”. Tissue Antigens. 41 (4): 190–5. PMID 8362411.
  3. ↑ derived from IMGT/HLA
  4. ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 4.15 4.16 4.17 4.18 4.19 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). “New allele frequency database: http://www.allelefrequencies.net“. Tissue Antigens. 61 (5): 403–7. PMID 12753660. External link in |title= (help)

Template:HLAB


Template:WikiDoc Sources