
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Haff disease natural history, complications and prognosis
Introduction
Overview
Overview
Haff disease has an incubation period of eight hours and presents with nausea, vomiting, muscle rigidity, chest pain, diaphoresis, and brown urine. Though it is a self-limiting condition with a good prognosis, some cases may develop complications such as acute kidney injury and disseminated intravascular coagulation.
Natural history, Complications and Prognosis
Natural history, Complications and Prognosis
- As Haff disease is a rare clinical syndrome, it is oftentimes misdiagnosed. Early diagnosis and treatment are required to prevent the development of complications.
- It has an incubation period of eight hours and presents with nausea, vomiting, myalgias, muscle rigidity, chest pain (mimicking myocardial infarction), diaphoresis, dyspnea, and brown urine indicating myoglobinuria. As it is a self limiting condition with good prognosis, most patients recover in 2-5 days. Haff disease is rarely associated with mortality, but some cases may develop complications such as acute kidney injury and disseminated intravascular coagulation. [1] [2]
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S
