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Hairy cell leukemia epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2], James Nasr[3]; Grammar Reviewer: Natalie Harpenau, B.S.[4]

Overview

Overview

Hairy cell leukemia is relatively rare, accounting for 1.4% of all lymphomas. The incidence of hairy cell leukemia is approximately 2.8-3.0 per 1,000,000 individuals in the United States. The incidence of hairy cell leukemia increases with age. The median age range at diagnosis of hairy cell leukemia is 55 to 60 years. Males are more commonly affected with hairy cell leukemia than females. The male to female ratio is approximately 4 to 1.

Epidemiology and Demographics

Epidemiology and Demographics

Prevalence

Incidence

Age

Gender

  • Males are more commonly affected with hairy cell leukemia than females.
  • The male to female ratio is approximately 4 to 1.[3]

Race

References

References

  1. 1.0 1.1 Teras LR, DeSantis CE, Cerhan JR, Morton LM, Jemal A, Flowers CR. 2016 US lymphoid malignancy statistics by World Health Organization subtypes. CA Cancer J Clin. 2016 Nov 12;66(6):443-459. doi: 10.3322/caac.21357. Epub 2016 Sep 12. PMID: 27618563.
  2. Epperla N, Zhao Q, Anghelina M, Neal J, Blachly JS, Rogers KA, Lozanski G, Oakes CC, Bhat SA, Zent CS, Banerji V, Grever M, Andritsos LA. Impact of sex on outcomes in patients with hairy cell leukemia. An HCL patient data registry analysis. Am J Hematol. 2023 May;98(5):E116-E118. doi: 10.1002/ajh.26881. Epub 2023 Feb 24. PMID: 36808760.
  3. Epperla N, Zhao Q, Anghelina M, Neal J, Blachly JS, Rogers KA, Lozanski G, Oakes CC, Bhat SA, Zent CS, Banerji V, Grever M, Andritsos LA. Impact of sex on outcomes in patients with hairy cell leukemia. An HCL patient data registry analysis. Am J Hematol. 2023 May;98(5):E116-E118. doi: 10.1002/ajh.26881. Epub 2023 Feb 24. PMID: 36808760.
  4. Tadmor T, Polliack A (December 2015). “Epidemiology and environmental risk in hairy cell leukemia”. Best Pract Res Clin Haematol. 28 (4): 175–9. doi:10.1016/j.beha.2015.10.014. PMID 26614895.


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