Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Hemophagocytic lymphohistiocytosis natural history, complications and prognosis
Introduction
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Overview
Overview
Natural History
Natural History
Complications
Complications
- Complications include
- Immunodeficiency
- Blindness
- Coma
- Leukemia and lymphoma
- Posterior reversible encephalopathy syndrome
Prognosis
Prognosis
- Secondary HLH in some individuals may be self-limited because patients are able to fully recover after having received only supportive medical treatment. However, long-term remission without the use of cytotoxic and immune-suppressive therapies is unlikely in the majority of adults with HLH and in those with CNS involvement.
- Without treatment, most people with familial hemophagocytic lymphohistiocytosis survive only a few months.
References
References
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]