Hemosiderosis natural history, complications and prognosis

The clinical spectrum of IPH ranges from asymptomatic cases to a chronic cough and dyspnea to repetitive hemoptysis with fatigue, anemia, and slowly progressive dyspnea and life-threatening acute respiratory failure. Common complications of IPH include Iron deficiency anemia and pulmonary fibrosis. Prognosis is generally variable, and the mean survival rate of patients with IPH is 2.5 to 5 years after diagnosis. Deaths can occur from acute massive hemorrhage or after progressive pulmonary insufficiency and right heart failure.

• The clinical spectrum of IPH ranges from asymptomatic cases to a chronic cough and dyspnea to repetitive hemoptysis with fatigue, anemia, and slowly progressive dyspnea and life-threatening acute respiratory failure.

• Common complications of IPH include:
• Iron deficiency anemia
• Pulmonary fibrosis

• Prognosis is generally variable
• The mean survival rate of patients with IPH is 2.5 to 5 years after diagnosis.
• Deaths can occur from acute massive hemorrhage or after progressive pulmonary insufficiency and right heart failure.

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