Common physical examination findings of IPH include tachypnea, pallor during the acute phase, and hepatosplenomegaly, failure to thrive and weight loss, and signs of respiratory failure such as digital clubbing in the chronic phase in severe cases.

Between the episodes of pulmonary hemorrhages, patients may remain well but commonly there is chronic ill-health. Physical examination findings vary depending on whether it is an acute or chronic presentation.

• In the acute phase, the physical examination may be completely normal or include respiratory signs such as tachypnea, pallor.
• In the chronic phase, there may be:
• Failure to thrive
• Weight loss
• Hepatosplenomegaly
• Digital clubbing and other signs of chronic hypoxia in the setting of pulmonary fibrosis
• Right heart failure