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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Hepatic fructokinase

Introduction

Hepatic fructokinase (or ketohexokinase) is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate.

ATP + Fru  <math>\longrightarrow</math>  ADP + F1P
ATP + D-fructose → ADP + D-fructose-1-phosphate[1]
Pathology

Pathology

A deficiency is associated with essential fructosuria.

References

References

  1. ↑ Bais R, James HM, Rofe AM, Conyers RA (1985). “The purification and properties of human liver ketohexokinase. A role for ketohexokinase and fructose-bisphosphate aldolase in the metabolic production of oxalate from xylitol”. Biochem. J. 230 (1): 53–60. PMC 1152585. PMID 2996495.
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