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Hepatic fructokinase

Hepatic fructokinase (or ketohexokinase) is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate.


ATP + Fru  <math>\longrightarrow</math>  ADP + F1P
ATP + D-fructose → ADP + D-fructose-1-phosphate[1]
Pathology

Pathology

A deficiency is associated with essential fructosuria.

References

References

  1. ↑ Bais R, James HM, Rofe AM, Conyers RA (1985). “The purification and properties of human liver ketohexokinase. A role for ketohexokinase and fructose-bisphosphate aldolase in the metabolic production of oxalate from xylitol”. Biochem. J. 230 (1): 53–60. PMC 1152585. PMID 2996495.
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