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Histamine dihydrochloride

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rabin Bista, M.B.B.S. [2]

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NOTE: Most over the counter (OTC) are not reviewed and approved by the FDA. However, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

Overview

Overview

Histamine dihydrochloride is a OTC granule that is FDA approved for the treatment of symptoms associated with allergic reactions and Helps support healthy respiratory system. Common adverse reactions include breathing difficulties, chills, cough, diarrhoea, flushing, headaches.

Adult Indications and Dosage

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Indications

  • Helps support healthy respiratory system and alleviates symptoms associated with allergic reactions

Dosage

  • Adults: Take five granules three times daily or as recommended by your healthcare practitioner.
  • Children: Take three granules and follow adult directions.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Histamine dihydrochloride in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Histamine dihydrochloride in adult patients.

Pediatric Indications and Dosage

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

Dosage

Children: Take three granules and follow adult directions.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Histamine dihydrochloride in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Histamine dihydrochloride in pediatric patients.

Contraindications

Contraindications

  • Condition1
Warnings

Warnings

  • If pregnant or breastfeeding, ask a health professional before use.
  • Keep out of reach of children.
  • In case of overdose, get medical help or contact a Poison Control Center right away.
Adverse Reactions

Adverse Reactions

Clinical Trials Experience

breathing difficulties, chills, cough, diarrhoea, flushing, headaches

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Histamine dihydrochloride in the drug label.

Drug Interactions

Drug Interactions

There is limited information regarding Histamine dihydrochloride Drug Interactions in the drug label.

Use in Specific Populations

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • If pregnant or breastfeeding, ask a health professional before use.


Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Histamine dihydrochloride in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Histamine dihydrochloride during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Histamine dihydrochloride with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Histamine dihydrochloride with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Histamine dihydrochloride with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Histamine dihydrochloride with respect to specific gender populations.

Race

There is no FDA guidance on the use of Histamine dihydrochloride with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Histamine dihydrochloride in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Histamine dihydrochloride in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Histamine dihydrochloride in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Histamine dihydrochloride in patients who are immunocompromised.

Administration and Monitoring

Administration and Monitoring

Administration

  • Oral

Monitoring

There is limited information regarding Monitoring of Histamine dihydrochloride in the drug label.

IV Compatibility

IV Compatibility

There is limited information regarding IV Compatibility of Histamine dihydrochloride in the drug label.

Overdosage

Overdosage

  • In case of overdose, get medical help or contact a Poison Control Center right away.
Pharmacology

Pharmacology

Mechanism of Action

    Structure

    Active Ingredient
    • HISTAMINUM HYDROCHLORICUM (Histamine hydrochloride) 15CH GR
    • HISTAMINUM HYDROCHLORICUM (Histamine hydrochloride) 200K GR
    • HISTAMINUM HYDROCHLORICUM (Histamine hydrochloride) 30K GR
    • HISTAMINUM HYDROCHLORICUM (Histamine hydrochloride) 5CH GR
    • HISTAMINUM HYDROCHLORICUM (Histamine hydrochloride) 6CH GR
    • HISTAMINUM HYDROCHLORICUM (Histamine hydrochloride) 9CH GR
    Inactive Ingredients
    • Lactose,
    • sucrose.

    Pharmacodynamics

    There is limited information regarding Pharmacodynamics of Histamine dihydrochloride in the drug label.

    Pharmacokinetics

    There is limited information regarding Pharmacokinetics of Histamine dihydrochloride in the drug label.

    Nonclinical Toxicology

    There is limited information regarding Nonclinical Toxicology of Histamine dihydrochloride in the drug label.

    Clinical Studies

    Clinical Studies

    There is limited information regarding Clinical Studies of Histamine dihydrochloride in the drug label.

    How Supplied

    How Supplied

      Storage

      There is limited information regarding Histamine dihydrochloride Storage in the drug label.

      Images

      Images

      Drug Images

      {{#ask: Page Name::Histamine dihydrochloride |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}

      Package and Label Display Panel

      PRINCIPAL DISPLAY PANEL

      This image is provided by the National Library of Medicine.

      UNDA

      Do not use if label perforation is broken

      Homeopathic Remedy

      NDC : 62106-5986-4

      HISTAMINUM HYDROCHLORICUM

      Histamine hydrochloride

      140 granules

      Indications

      Helps support healthy respiratory system and alleviates symptoms associated with allergic reactions

      Ingrediendts and Appearance

      This image is provided by the National Library of Medicine.

      {{#ask: Label Page::Histamine dihydrochloride |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}

      Patient Counseling Information

      Patient Counseling Information

      QUESTIONS? 1-888-737-6925.

      Precautions with Alcohol

      Precautions with Alcohol

      • Alcohol-Histamine dihydrochloride interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
      Brand Names

      Brand Names

      • HISTAMINUM HYDROCHLORICUM®[1]
      Look-Alike Drug Names

      Look-Alike Drug Names

      There is limited information regarding Histamine dihydrochloride Look-Alike Drug Names in the drug label.

      Drug Shortage Status
      Price

      Price

      References

      References

      The contents of this FDA label are provided by the National Library of Medicine.

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