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Hyperchloremic acidosis

Introduction

Overview

Overview

Usually the HCO3– lost is replaced by a chloride anion, and thus there is a normal anion gap. In normal anion gap acidosis, the increased anion is chloride, which is measured, so the anion gap does not increase. Thus, normal anion gap acidosis is also known as hyperchloremic acidosis. Urine anion gap is useful in evaluating a patient with a normal anion gap.

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Historical Perspective

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References

Pathophysiology

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References

Causes

Overview

Causes

The mnemonic for the most common causes of a normal-anion gap metabolic acidosis is “DURHAM.”

  • D– Diarrhea
  • U– Ureteral diversion
  • R– Renal tubular acidosis
  • H– Hyperailmentation
  • A– Addison’s disease, acetazolamide, ammonium chloride
  • M– Miscellaneous (chloridorrhea, amphotericin B, toluene – toluene causes high anion gap metabolic acidosis followed by normal anion gap metabolic acidosis.

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Epidemiology and Demographics

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References

Natural History, Complications and Prognosis

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References

Diagnosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Ultrasound

Treatment

Treatment

Medical Therapy

Contraindicated medications

Hyperchloremic acidosis is considered an absolute contraindication to the use of the following medications:

Case Studies

Case Studies

Case#1

Related Chapters
External links


Template:WikiDoc Sources

Editor-In-Chief: Template:DiseaseDisorder infobox C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.D. [2]