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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Hyperparathyroidism ultrasound

Introduction

Overview

Overview

Neck ultrasound is used for preoperative localization of hyper-functioning parathyroid gland. Neck ultrasound alone is not a sensitive investigation for this purpose. Neck ultrasound along with Tc-99m sestamibi scintigraphy is most common used diagnostic modality for preoperative localization of hyper-functioning parathyroid gland.

Ultrasound

Ultrasound

  • Neck ultrasound is used for preoperative localization of hyper-functioning parathyroid gland. Neck ultrasound alone is not a sensitive investigation for this purpose. [1]
  • Neck ultrasound is an operator dependent method.
  • Neck ultrasound along with Tc-99m sestamibi scintigraphy is most common used diagnostic modality for preoperative localization of hyper-functioning parathyroid gland.[2]
  • Presence of thyroid nodule may lead to false positive results.[3]
  • Ultrasound is the single most cost-effective method used for preoperative localization of hyper-functioning parathyroid gland followed by 4-dimentional CT.[4]
  • Surgeon performed ultrasound has a sensitivity of 69% to 92.5%.[5][6][7][8]
Neck ultrasound showing parathyroid adenoma – Source:By Hellerhoff (Own work), via Wikimedia Commons
References

References

  1. ↑ Haber RS, Kim CK, Inabnet WB (2002). “Ultrasonography for preoperative localization of enlarged parathyroid glands in primary hyperparathyroidism: comparison with (99m)technetium sestamibi scintigraphy”. Clin. Endocrinol. (Oxf). 57 (2): 241–9. PMID 12153604.
  2. ↑ Elaraj DM, Sippel RS, Lindsay S, Sansano I, Duh QY, Clark OH, Kebebew E (2010). “Are additional localization studies and referral indicated for patients with primary hyperparathyroidism who have negative sestamibi scan results?”. Arch Surg. 145 (6): 578–81. doi:10.1001/archsurg.2010.108. PMID 20566979.
  3. ↑ Barbaros U, Erbil Y, SalmashoÄŸlu A, IÅŸsever H, Aral F, Tunaci M, OzarmaÄŸan S (2009). “The characteristics of concomitant thyroid nodules cause false-positive ultrasonography results in primary hyperparathyroidism”. Am J Otolaryngol. 30 (4): 239–43. doi:10.1016/j.amjoto.2008.06.007. PMID 19563934.
  4. ↑ Lubitz CC, Stephen AE, Hodin RA, Pandharipande P (2012). “Preoperative localization strategies for primary hyperparathyroidism: an economic analysis”. Ann. Surg. Oncol. 19 (13): 4202–9. doi:10.1245/s10434-012-2512-2. PMC 3680347. PMID 22825773.
  5. ↑ Solorzano CC, Carneiro-Pla DM, Irvin GL (2006). “Surgeon-performed ultrasonography as the initial and only localizing study in sporadic primary hyperparathyroidism”. J. Am. Coll. Surg. 202 (1): 18–24. doi:10.1016/j.jamcollsurg.2005.08.014. PMID 16377493.
  6. ↑ Prasannan S, Davies G, Bochner M, Kollias J, Malycha P (2007). “Minimally invasive parathyroidectomy using surgeon-performed ultrasound and sestamibi”. ANZ J Surg. 77 (9): 774–7. doi:10.1111/j.1445-2197.2007.04227.x. PMID 17685957.
  7. ↑ Chapuis Y, Fulla Y, Bonnichon P, Tarla E, Abboud B, Pitre J, Richard B (1996). “Values of ultrasonography, sestamibi scintigraphy, and intraoperative measurement of 1-84 PTH for unilateral neck exploration of primary hyperparathyroidism”. World J Surg. 20 (7): 835–9, discussion 839–40. PMID 8678959.
  8. ↑ Casas AT, Burke GJ, Sathyanarayana, Mansberger AR, Wei JP (1993). “Prospective comparison of technetium-99m-sestamibi/iodine-123 radionuclide scan versus high-resolution ultrasonography for the preoperative localization of abnormal parathyroid glands in patients with previously unoperated primary hyperparathyroidism”. Am. J. Surg. 166 (4): 369–73. PMID 8214295.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]