Hypertensive nephropathy classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]Nasrin Nikravangolsefid, MD-MPH [3]

Classification

Hypertensive nephropathy is classified according to disease severity and histological finding into two subtypes^[1]:

Benign nephrosclerosis
- It often occurs in the benign phase of essential hypertension.
- It is characterized by Hyaline accumulation in the renal arterioles leading to afferent arteriolar narrowing.

Malignant nephrosclerosis
- It occurs in the malignant phase of essential hypertension, which is defined by a sudden elevation of blood pressure along with multi-organ damage such as papilledema, central nervous system involvement, cardiac decompensation, and progressive renal failure.
- It is characterized by fibrinoid necrosis in the afferent arterioles.

References

↑ Ono, Hidehiko; Ono, Yuko (1997). “NEPHROSCLEROSIS AND HYPERTENSION”. Medical Clinics of North America. 81 (6): 1273–1288. doi:10.1016/S0025-7125(05)70582-4. ISSN 0025-7125.

Classification