Hypertensive nephropathy medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Nasrin Nikravangolsefid, MD-MPH [2]

Medical therapy[1]

Medical therapy^[1]

Non-pharmacological therapy
- Lifestyle modification and decreased salt intake
  - Sodium intake < 50 mmol/day (3 g/day of salt) leads to reduce systolic blood pressure by 10 mmHg.
  - Sodium intake< 100 mmol/day (6 g/day of salt) has been found to decrease proteinuria by 25%.
- Weight loss
Pharmacological therapy to control hypertension includes:
- ACE inhibitors or ARB
- Diuretics: loop diuretics and thiazides
- Calcium channel blockers
- Beta blockers
- Alpha blockers
- Mineralocorticoid receptor blockers
- Renin inhibitors

References

↑ Pugh, Dan; Gallacher, Peter J.; Dhaun, Neeraj (2019). “Management of Hypertension in Chronic Kidney Disease”. Drugs. 79 (4): 365–379. doi:10.1007/s40265-019-1064-1. ISSN 0012-6667.