Hypogonadism epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

The prevalence of hypogonadism in men is estimated to be 38,700 per 100,000 individual aging 45 years. The incidence of hypogonadism is 1230 per 100,000 persons. Hypogonadism affects men more than women and its prevalence increases with age.^[1]

Epidemiology and demographics

Prevalence

The prevalence of hypogonadism in men is 38,700 per 100,000 persons aged 45 years.^[2]
The prevalence of androgen deficiency ranges from a low of 6,000 per 100,000 persons aged 40 years to a high of 12,000 per 100,000 persons aging 70 years.^[1]
There are no sufficient prevalence results for hypogonadism in women.

Incidence

The incidence of hypogonadism is 1230 per 100,000 persons.^[1] The rate may be increasing^[3]^[4].

Gender

Hypogonadism is more common in the males than females.

Age

The prevalence of hypogonadism increases with age.

Race

There is no racial predilection of hypogonadism.

References

↑ ^1.0 ^1.1 ^1.2 Araujo AB, O’Donnell AB, Brambilla DJ, Simpson WB, Longcope C, Matsumoto AM; et al. (2004). “Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study”. J Clin Endocrinol Metab. 89 (12): 5920–6. doi:10.1210/jc.2003-031719. PMID 15579737.
↑ Mulligan T, Frick MF, Zuraw QC, Stemhagen A, McWhirter C (2006). “Prevalence of hypogonadism in males aged at least 45 years: the HIM study”. Int J Clin Pract. 60 (7): 762–9. doi:10.1111/j.1742-1241.2006.00992.x. PMC 1569444. PMID 16846397.
↑ Bhasin S (2007). “Secular decline in male reproductive function: Is manliness threatened?”. J Clin Endocrinol Metab. 92 (1): 44–5. doi:10.1210/jc.2006-2438. PMID 17209224.
↑ Lokeshwar SD, Patel P, Fantus RJ, Halpern J, Chang C, Kargi AY; et al. (2021). “Decline in Serum Testosterone Levels Among Adolescent and Young Adult Men in the USA”. Eur Urol Focus. 7 (4): 886–889. doi:10.1016/j.euf.2020.02.006. PMID 32081788 Check |pmid= value (help).

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[pmid15579737-1] 1.0 ^1.1 ^1.2 Araujo AB, O’Donnell AB, Brambilla DJ, Simpson WB, Longcope C, Matsumoto AM; et al. (2004). “Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study”. J Clin Endocrinol Metab. 89 (12): 5920–6. doi:10.1210/jc.2003-031719. PMID 15579737.

[pmid16846397-2] Mulligan T, Frick MF, Zuraw QC, Stemhagen A, McWhirter C (2006). “Prevalence of hypogonadism in males aged at least 45 years: the HIM study”. Int J Clin Pract. 60 (7): 762–9. doi:10.1111/j.1742-1241.2006.00992.x. PMC 1569444. PMID 16846397.

[pmid17209224-3] Bhasin S (2007). “Secular decline in male reproductive function: Is manliness threatened?”. J Clin Endocrinol Metab. 92 (1): 44–5. doi:10.1210/jc.2006-2438. PMID 17209224.

[pmid32081788-4] Lokeshwar SD, Patel P, Fantus RJ, Halpern J, Chang C, Kargi AY; et al. (2021). “Decline in Serum Testosterone Levels Among Adolescent and Young Adult Men in the USA”. Eur Urol Focus. 7 (4): 886–889. doi:10.1016/j.euf.2020.02.006. PMID 32081788 Check |pmid= value (help).

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