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Hypomagnesemia electrocardiogram

Introduction

Overview

Overview

ECG changes are non-specific and include a slight prolongation of conduction (a prolonged QT interva) and the depression of the ST segment. Magnesium depletion increases susceptibility to arrhythmogenic effects of drugs such as isoproterenol and cardiac glycosides and this includes supraventricular and ventricular arrhythmias. Torsade de pointes (repetitive polymorphous ventricular tachycardia with prolongation of QT interval) has been reported in cases of hypomagnesaemia. Torsade de pointes and other arrhythmias have been successfully treated with magnesium. However, this may be a pharmacological effect, independent of underlying magnesium deficiency.

Electrocardiogram

Electrocardiogram

ECG changes are non-specific and include:[1][2]

  • A slight prolongation of conduction and the depression of the ST segment
  • Magnesium depletion increases susceptibility to arrhythmogenic effects of drugs such as isoproterenol and cardiac glycosides and this includes:
    • Supraventricular and ventricular arrhythmias
    • Torsade de pointes has been reported in cases of hypomagnesaemia
  • Torsade de pointes and other arrhythmias have been successfully treated with magnesium. However, this may be a pharmacological effect, independent of underlying magnesium deficiency.
References

References

  1. ↑ Varon ME, Sherer DM, Abramowicz JS, Akiyama T (1992). “Maternal ventricular tachycardia associated with hypomagnesemia”. Am J Obstet Gynecol. 167 (5): 1352–5. doi:10.1016/s0002-9378(11)91715-3. PMID 1442989.
  2. ↑ Millane TA, Ward DE, Camm AJ (1992). “Is hypomagnesemia arrhythmogenic?”. Clin Cardiol. 15 (2): 103–8. doi:10.1002/clc.4960150210. PMID 1371093.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]