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Hypoparathyroidism epidemiology and demographics

Introduction

Overview

Overview

In Denmark, the incidence of postsurgical hypoparathyroidism is approximately 0.8 per 100,000 person-years. In United States, the prevalence of hypoparathyroidism is approximately 37 per 100,000 person-years. Majority of patients with hypoparathyroidism are 45 years or older. The women to men ratio is approximately 3 to 1.

Epidemiology and Demographics

Epidemiology and Demographics

Incidence

  • In Denmark, the incidence of postsurgical hypoparathyroidism is approximately 0.8 per 100,000 person-years.[1]

Prevalence

  • In United States, the prevalence of hypoparathyroidism is approximately 37 per 100,000 person-years.[2]
  • In Denmark, the prevalence of postsurgical hypoparathyroidism is approximately 22 per 100,000 person-years.[2]
  • In Denmark, the prevalence of nonsurgical hypoparathyroidism is approximately 2.3 per 100,000 person-years.[3]
  • In Japan, the prevalence of idiopathic hypoparathyroidism ranges from a low of 55 per 100,000 persons to a high of 88 per 100,000 persons with an average prevalence of 72 per 100,000 persons.[4]
  • In Japan, the prevalence of pseudohypoparathyroidism ranges from a low of 0.26 per 100,000 persons to a high of 0.42 per 100,000 persons with an average prevalence of 0.34 per 100,000 persons.[4]

Age

  • Majority of patients with hypoparathyroidism are 45 years or older.[5]

Gender

  • Women are more commonly affected by hypoparathyroidism than men. The women to men ratio is approximately 3 to 1.[5]
References

References

  1. ↑ Underbjerg L, Sikjaer T, Mosekilde L, Rejnmark L (2013). “Cardiovascular and renal complications to postsurgical hypoparathyroidism: a Danish nationwide controlled historic follow-up study”. J Bone Miner Res. 28 (11): 2277–85. doi:10.1002/jbmr.1979. PMIDΒ 23661265.
  2. ↑ 2.0 2.1 Clarke BL, Brown EM, Collins MT, JΓΌppner H, Lakatos P, Levine MA, Mannstadt MM, Bilezikian JP, Romanischen AF, Thakker RV (2016). “Epidemiology and Diagnosis of Hypoparathyroidism”. J. Clin. Endocrinol. Metab. 101 (6): 2284–99. doi:10.1210/jc.2015-3908. PMCΒ 5393595. PMIDΒ 26943720.
  3. ↑ Underbjerg L, Sikjaer T, Mosekilde L, Rejnmark L (2015). “The Epidemiology of Nonsurgical Hypoparathyroidism in Denmark: A Nationwide Case Finding Study”. J. Bone Miner. Res. 30 (9): 1738–44. doi:10.1002/jbmr.2501. PMIDΒ 25753591.
  4. ↑ 4.0 4.1 Nakamura Y, Matsumoto T, Tamakoshi A, Kawamura T, Seino Y, Kasuga M, Yanagawa H, Ohno Y (2000). “Prevalence of idiopathic hypoparathyroidism and pseudohypoparathyroidism in Japan”. J Epidemiol. 10 (1): 29–33. PMIDΒ 10695258.
  5. ↑ 5.0 5.1 Powers J, Joy K, Ruscio A, Lagast H (2013). “Prevalence and incidence of hypoparathyroidism in the United States using a large claims database”. J. Bone Miner. Res. 28 (12): 2570–6. doi:10.1002/jbmr.2004. PMIDΒ 23737456.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]