Hypopituitarism epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2], Iqra Qamar M.D.[3]

Overview

In a longitudinal survey (1992-1999), the incidence of hypopituitarism was estimated to be 4.2 cases per 100,000. A study comprising two cross-sectional surveys showed the prevalence of hypopituitarism to be 29 – 45.5 per 100.000 individual.

Epidemiology and Demographics

There is one study performed in northern Spain, regarding hypopituitarism epidemiology combining two cross-sectional surveys (from 1992 and 1999).^[1]

Incidence

In a longitudinal survey (1992-1999), the incidence of hypopituitarism was estimated to be 4.2 cases per 100,000.^[1]
A study was done to find out etiological distribution among 773 adults with hypopituitarism that showed:^[2]
- Non-tumoral etiology (50%)
- Pituitary tumors (43.6 %)
- Extra-pituitary tumors (7.2%)

Prevalence

There is a limited information regarding the prevalence of hypopituitarism.
The prevalence of hypopituitarism was found to be 29 – 45.5 per 100,000 individual in the two cross-sectional studies.^[1]

Gender

Men and women are affected equally by hypopituitarism.

Age

Hypopituitarism occurs at any age.

Race

There is no racial predilection for hypopituitarism.

References

↑ ^1.0 ^1.1 ^1.2 Regal M, Páramo C, Sierra SM, Garcia-Mayor RV (2001). “Prevalence and incidence of hypopituitarism in an adult Caucasian population in northwestern Spain”. Clin. Endocrinol. (Oxf). 55 (6): 735–40. PMID 11895214.
↑ Tanriverdi F, Dokmetas HS, Kebapcı N, Kilicli F, Atmaca H, Yarman S, Ertorer ME, Erturk E, Bayram F, Tugrul A, Culha C, Cakir M, Mert M, Aydin H, Taskale M, Ersoz N, Canturk Z, Anaforoglu I, Ozkaya M, Oruk G, Hekimsoy Z, Kelestimur F, Erbas T (2014). “Etiology of hypopituitarism in tertiary care institutions in Turkish population: analysis of 773 patients from Pituitary Study Group database”. Endocrine. 47 (1): 198–205. doi:10.1007/s12020-013-0127-4. PMID 24366641.

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[pmid11895214-1] 1.0 ^1.1 ^1.2 Regal M, Páramo C, Sierra SM, Garcia-Mayor RV (2001). “Prevalence and incidence of hypopituitarism in an adult Caucasian population in northwestern Spain”. Clin. Endocrinol. (Oxf). 55 (6): 735–40. PMID 11895214.

[pmid24366641-2] Tanriverdi F, Dokmetas HS, Kebapcı N, Kilicli F, Atmaca H, Yarman S, Ertorer ME, Erturk E, Bayram F, Tugrul A, Culha C, Cakir M, Mert M, Aydin H, Taskale M, Ersoz N, Canturk Z, Anaforoglu I, Ozkaya M, Oruk G, Hekimsoy Z, Kelestimur F, Erbas T (2014). “Etiology of hypopituitarism in tertiary care institutions in Turkish population: analysis of 773 patients from Pituitary Study Group database”. Endocrine. 47 (1): 198–205. doi:10.1007/s12020-013-0127-4. PMID 24366641.

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