Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Hypopituitarism historical perspective
Introduction
Overview
Overview
Hypopituitarism was first described by Dr. Simmonds for the first time in 1914. Dr. Yalow and Berson discovered the radioimmunoassay, in 1950. Causes of the hypopituitarism were being described through the 20th and 21st centuries.
Historical Perspective
Historical Perspective
- In 1914, Dr. Simmonds was the first one to describe hypopituitarism. He described it as the inability of the pituitary gland to secrete hormones matching the organs need.[1]
- In 1950, Dr. Yalow and Berson discovered the radioimmunoassay, which helped with the measurement of the pituitary hormones for the diagnosis of hypopituitarism. Previously, it was based on only the presenting signs and symptoms of the patients.[2]
- In 1973, combined stimulation tests of insulin, gonadotrophin releasing hormone (GnRH), and thyroid releasing hormone (TRH) were performed for the first time, to assess the pituitary gland function.[3]
- Through the 20th and 21st centuries, causes of the hypopituitarism were further explained.
References
References
- ↑ Schneider HJ, Aimaretti G, Kreitschmann-Andermahr I, Stalla GK, Ghigo E (2007). “Hypopituitarism”. Lancet. 369 (9571): 1461–70. doi:10.1016/S0140-6736(07)60673-4. PMID 17467517.
- ↑ Prozesky OW (1979). “Measles vaccination”. S Afr Med J. 55 (7): 236. PMID 441860.
- ↑ Harsoulis P, Marshall JC, Kuku SF, Burke CW, London DR, Fraser TR (1973). “Combined test for assessment of anterior pituitary function”. Br Med J. 4 (5888): 326–9. PMC 1587416. PMID 4202260.
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]