
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
IGSF8
Introduction
Immunoglobulin superfamily member 8 is a protein that in humans is encoded by the IGSF8 gene.[1][2][3] IGSF8 has also been designated as CD316 (cluster of differentiation 316).
References
References
- β Stipp CS, Kolesnikova TV, Hemler ME (Oct 2001). “EWI-2 is a major CD9 and CD81 partner and member of a novel Ig protein subfamily”. J Biol Chem. 276 (44): 40545β54. doi:10.1074/jbc.M107338200. PMIDΒ 11504738.
- β Clark KL, Zeng Z, Langford AL, Bowen SM, Todd SC (Oct 2001). “PGRL is a major CD81-associated protein on lymphocytes and distinguishes a new family of cell surface proteins”. J Immunol. 167 (9): 5115β21. doi:10.4049/jimmunol.167.9.5115. PMIDΒ 11673522.
- β “Entrez Gene: IGSF8 immunoglobulin superfamily, member 8”.
Further reading
Further reading
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899β903. doi:10.1073/pnas.242603899. PMCΒ 139241. PMIDΒ 12477932.
- Charrin S, Le Naour F, Labas V, et al. (2003). “EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells”. Biochem. J. 373 (Pt 2): 409β21. doi:10.1042/BJ20030343. PMCΒ 1223506. PMIDΒ 12708969.
- Zhang XA, Lane WS, Charrin S, et al. (2003). “EWI2/PGRL associates with the metastasis suppressor KAI1/CD82 and inhibits the migration of prostate cancer cells”. Cancer Res. 63 (10): 2665β74. PMIDΒ 12750295.
- Bonkobara M, Das A, Takao J, et al. (2003). “Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes”. Br. J. Dermatol. 148 (4): 654β64. doi:10.1046/j.1365-2133.2003.05244.x. PMIDΒ 12752121.
- Stipp CS, Kolesnikova TV, Hemler ME (2004). “EWI-2 regulates alpha3beta1 integrin-dependent cell functions on laminin-5”. J. Cell Biol. 163 (5): 1167β77. doi:10.1083/jcb.200309113. PMCΒ 2173626. PMIDΒ 14662754.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40β5. doi:10.1038/ng1285. PMIDΒ 14702039.
- Kolesnikova TV, Stipp CS, Rao RM, et al. (2004). “EWI-2 modulates lymphocyte integrin alpha4beta1 functions”. Blood. 103 (8): 3013β9. doi:10.1182/blood-2003-07-2201. PMIDΒ 15070678.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121β7. doi:10.1101/gr.2596504. PMCΒ 528928. PMIDΒ 15489334.
- Yang XH, Kovalenko OV, Kolesnikova TV, et al. (2006). “Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization”. J. Biol. Chem. 281 (18): 12976β85. doi:10.1074/jbc.M510617200. PMIDΒ 16537545.
- Sala-ValdΓ©s M, Ursa A, Charrin S, et al. (2006). “EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins”. J. Biol. Chem. 281 (28): 19665β75. doi:10.1074/jbc.M602116200. PMIDΒ 16690612.
- Kettner S, Kalthoff F, Graf P, et al. (2007). “EWI-2/CD316 is an inducible receptor of HSPA8 on human dendritic cells”. Mol. Cell. Biol. 27 (21): 7718β26. doi:10.1128/MCB.00180-07. PMCΒ 2169036. PMIDΒ 17785435.
External links
External links
- IGSF8+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
