Health Dictionary Find a Doctor

IKZF4

Zinc finger protein Eos is a protein that in humans is encoded by the IKZF4 gene.[1][2]

Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM][2]

Interactions

Interactions

IKZF4 has been shown to interact with CTBP1[3] and IKZF1.[1][4]

References

References

  1. 1.0 1.1 Perdomo J, Holmes M, Chong B, Crossley M (Jan 2001). “Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities”. J Biol Chem. 275 (49): 38347–54. doi:10.1074/jbc.M005457200. PMID 10978333.
  2. 2.0 2.1 “Entrez Gene: IKZF4 IKAROS family zinc finger 4 (Eos)”.
  3. Perdomo, José; Crossley Merlin (Dec 2002). “The Ikaros family protein Eos associates with C-terminal-binding protein corepressors”. Eur. J. Biochem. Germany. 269 (23): 5885–92. doi:10.1046/j.1432-1033.2002.03313.x. ISSN 0014-2956. PMID 12444977.
  4. Honma, Y; Kiyosawa H; Mori T; Oguri A; Nikaido T; Kanazawa K; Tojo M; Takeda J; Tanno Y; Yokoya S; Kawabata I; Ikeda H; Wanaka A (Mar 1999). “Eos: a novel member of the Ikaros gene family expressed predominantly in the developing nervous system”. FEBS Lett. NETHERLANDS. 447 (1): 76–80. doi:10.1016/S0014-5793(99)00265-3. ISSN 0014-5793. PMID 10218586.
Further reading

Further reading



Looking for the patient version?

Back to the patient-friendly article

© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH