Health Dictionary
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INTS1
Introduction
Integrator complex subunit 1 is a protein that in humans is encoded by the INTS1 gene. [1]
Function
Function
INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).
Further reading
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.