Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Idiopathic pulmonary fibrosis surgery
Introduction
Overview
Overview
Lung transplantation is essential in treatment of patients with idiopathic pulmonary fibrosis. Pulmonary fibrosis is the most common interstitial lung disease requiring lung transplant and it should be performed early in order to increase the survival rate.
Indications
Indications
Indications of lung transplantation include:
- Patients younger than 65 years old
- Patients with low body mass index (<26 kg/m2)
Surgery
Surgery
Lung transplantation
- Lung transplantation is essential in treatment of patients with idiopathic pulmonary fibrosis. Pulmonary fibrosis is the most common interstitial lung disease requiring lung transplant and it should be performed early in order to increase the survival rate.[1]
- Time of referral to lung transplantation: [2]
- Confirmed histopathologic or radiographic findings of usual interstitial pneumonitis (UIP) regardless of lung function
- Forced vital capacity (FVC) <80% predicted
- Diffusion capacity of the lung for carbon monoxide (DLCO) <40% predicted.
- Lung functional limitation (eg, dyspnea)
- Time of listing:[3]
- Decline in FVC ≥10% during 6 months of follow-up
- Decline in DLCO ≥15% during 6 months of follow-up
- Development of pulmonary hypertension
- Hospitalization due to acute exacerbation
References
References
- ↑ Thabut G, Mal H, Castier Y, Groussard O, Brugière O, Marrash-Chahla R; et al. (2003). “Survival benefit of lung transplantation for patients with idiopathic pulmonary fibrosis”. J Thorac Cardiovasc Surg. 126 (2): 469–75. PMID 12928646.
- ↑ Weill D, Benden C, Corris PA, Dark JH, Davis RD, Keshavjee S; et al. (2015). “A consensus document for the selection of lung transplant candidates: 2014–an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation”. J Heart Lung Transplant. 34 (1): 1–15. doi:10.1016/j.healun.2014.06.014. PMID 25085497.
- ↑ Weill D, Benden C, Corris PA, Dark JH, Davis RD, Keshavjee S; et al. (2015). “A consensus document for the selection of lung transplant candidates: 2014–an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation”. J Heart Lung Transplant. 34 (1): 1–15. doi:10.1016/j.healun.2014.06.014. PMID 25085497.
[[Category:Primary Care]
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]