Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Idiopathic thrombocytopenic purpura history and symptoms
Introduction
Overview
Overview
History and Symptoms
History and Symptoms
ITP is chronic in adults[1] and the probability of remission is 20–40%.[2] , ITP patients suffer from bruising, petechiae, nosebleeds and bleeding gums may occur if the platelet count is below 20,000,[3] compared to a normal range of 150,000–400,000 per mm3.
Evans syndrome can occur in ~1% of cases and manifests by an autoimmune (Coombs +) hemolytic anemia with ITP.
Symptoms include:
- Abnormally heavy menstruation
- Bleeding into the skin causing a characteristic skin rash that looks like pinpoint red spots (petechial rash), purpura
- Easy bruising
- Nosebleed or bleeding in the mouth
- intracranial hemorrhage
References
References
- ↑ Cines DB, Blanchette VS (2002). “Immune thrombocytopenic purpura”. N. Engl. J. Med. 346 (13): 995–1008. doi:10.1056/NEJMra010501. PMID 11919310.
- ↑ Stevens W, Koene H, Zwaginga JJ, Vreugdenhil G (2006). “Chronic idiopathic thrombocytopenic purpura: present strategy, guidelines and new insights”. The Netherlands journal of medicine. 64 (10): 356–63. PMID 17122451.
- ↑ Cines DB, McMillan R (2005). “Management of adult idiopathic thrombocytopenic purpura”. Annu. Rev. Med. 56: 425–42. doi:10.1146/annurev.med.56.082103.104644. PMID 15660520.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]