Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Idiopathic thrombocytopenic purpura natural history, complications and prognosis
Introduction
Overview
Overview
Natural History
Natural History
More than 70% of the cases in children end up in remission within 6 months whether treated or not.[1][2][3] Moreover, a third of the remaining chronic cases remitted during the follow-up observation, and another third ended up with only mild thrombocytopenia (>50,000 platelets per ΞΌL).[1]
Complications
Complications
Subarachnoid, intracerebral hemorrhage or other internal bleeding are very serious possible complications of this disease. Fortunately, these are unlikely in patients with the platelets count above 20,000.
Prognosis
Prognosis
With treatment, the chance of remission (a symptom-free period) is good. Rarely, ITP may become a long-term condition in adults and reappear, even after a symptom-free period.
References
References
- β 1.0 1.1 Watts RG (2004). “Idiopathic thrombocytopenic purpura: a 10-year natural history study at the children’s hospital of alabama”. Clinical pediatrics. 43 (8): 691β702. PMIDΒ 15494875.
- β Treutiger I, Rajantie J, Zeller B, Henter JI, Elinder G, RosthΓΈj S (2007). “Does treatment of newly diagnosed idiopathic thrombocytopenic purpura reduce morbidity?”. Arch. Dis. Child. 92 (8): 704β7. doi:10.1136/adc.2006.098442. PMIDΒ 17460024.
- β Ou CY, Hsieh KS, Chiou YH, Chang YH, Ger LP (2006). “A comparative study of initial use of intravenous immunoglobulin and prednisolone treatments in childhood idiopathic thrombocytopenic purpur”. Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi. 47 (5): 226β31. PMIDΒ 17352309.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]