
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
IgA nephropathy historical perspective
Introduction
Overview
Overview
IgA nephropathy (Berger disease) was first described by Jean Berger, a pathologist, and Nicole Hinglais, an electron microscopist, in 1968 in France.
Historical Perspective
Historical Perspective
- In 1968, IgA nephropathy was first described by Jean Berger, a pathologist, and Nicole Hinglais, an electron microscopist, in France.[1][2][3][4]
- IgA nephropathy was originally described by Berger and Hinglais in 1968. In the original one-page article titled “Les depots intercapillaires d’IgA-IgG” in the “journal d’Urologie-Nephrologie”, the authors described the renal disease under light microscopy showing focal and segmental mesangial proliferation with expansion of the matrix. Under electron microscopy, they noted the predominance of IgA deposits in the renal mesangium that were associated with the presence of less significant presence of IgG and C3.
- In 1969, following the first description of IgA nephropathy, the association of IgA nephropathy with Henoch-Schönlein purpura was described by Berger.[1]
References
References
- ↑ 1.0 1.1 Berger J (1969). “IgA glomerular deposits in renal disease”. Transplant Proc. 1 (4): 939–44. PMID 4107073.
- ↑ Berger J, Hinglais N (1968). “[Intercapillary deposits of IgA-IgG]”. J Urol Nephrol (Paris). 74 (9): 694–5. PMID 4180586.
- ↑ Feehally J, Cameron JS (2011). “IgA nephropathy: progress before and since Berger”. Am J Kidney Dis. 58 (2): 310–9. doi:10.1053/j.ajkd.2011.03.024. PMID 21705126.
- ↑ Feehally, John; Cameron, J. Stewart (2011). “IgA Nephropathy: Progress Before and Since Berger”. American Journal of Kidney Diseases. 58 (2): 310–319. doi:10.1053/j.ajkd.2011.03.024. ISSN 0272-6386.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Ali Poyan Mehr, M.D. [2] Associate Editor(s)-in-Chief: Olufunmilola Olubukola M.D.[3]
