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Immune Thrombocytopenia epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maryam Barkhordarian, M.D.[2]

Overview

Overview

The incidence of Immune thrombocytopenia is approximately 1.6- 3.9 per 100,000 adult individuals worldwide and 1.1- 5.8 per 100,000 individuals among children. Patients of all age groups may develop Immune thrombocytopenia. The Prevalence of chronic Immune thrombocytopenia increases with age. Black and non-hispanic individuals are less likely to develop ITP.

Epidemiology and Demographics

Epidemiology and Demographics

Incidence

  • The incidence of Immune thrombocytopenia is approximately 1.6- 3.9 per 100,000 adult individuals worldwide and 1.1- 5.8 per 100,000 individuals among children. The overall incidence rate was higher in women (4.4 per 100,000 person year) than men ( 3.4 per 100,000 person year).Women are more commonly affected by Immune thrombocytopenia than men.
  • In year 2014, the incidence of Immune thrombocytopenia among French people is approximately 2.9/ 100,000 person years with higher incidence among women. The incidence has bimodal distribution with first peak among male children among 1-5 years and men over 75 years of age. However the distribution for women is constant.[1] [2]

Prevalence

  • The prevalence of chronic immune thrombocytopenia ( lasting longer than 12 months) is approximately 9.5-11.2 per 100,000 individuals in the United States.
  • In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
  • The prevalence of [disease/malignancy] is estimated to be [number] cases annually.

Case-fatality rate/Mortality rate

  • In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
  • The case-fatality rate/mortality rate of [disease name] is approximately [number range].

Age

  • Patients of all age groups may develop Immune thrombocytopenia.
  • The Prevalence of chronic Immune thrombocytopenia increases with age; the childhood ITP remits spontaneously.
  • Immune thrombocytopenia commonly affects individuals younger than 5 years of age.
  • [Chronic disease name] is usually first diagnosed among [age group].
  • [Acute disease name] commonly affects [age group].

Race

  • There is no racial predilection to [disease name].
  • Black and non-hispanic individuals are less likely to develop ITP, thereafter, the providers should suspect alternative diagnosis or secondary ITP in these races.[3]

Gender

  • [Disease name] affects men and women equally.
  • Women are more commonly affected by Immune thrombocytopenia than men.

Season

  • The majority of Immune thrombocytopenia cases are reported in January and the minority in summer in all age group probably due to viral infection..[1] [2]
  • [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].

Developed Countries

Developing Countries

References

References

  1. 1.0 1.1 Kohli, Rahil; Chaturvedi, Shruti (2019). “Epidemiology and Clinical Manifestations of Immune Thrombocytopenia”. Hämostaseologie. 39 (03): 238–249. doi:10.1055/s-0039-1683416. ISSN 0720-9355.
  2. 2.0 2.1 Schmoldt A, Benthe HF, Haberland G (1975). “Digitoxin metabolism by rat liver microsomes” Check |url= value (help). Biochem Pharmacol. 24 (17): 1639–41. PMID https://doi.org/10.1182/blood-2014-05-578336 Check |pmid= value (help).
  3. Kim, Taylor Olmsted; Grimes, Amanda B.; Kirk, Susan E.; Gilbert, Megan M.; Reed, Helen D.; Staggers, Kristen A.; Walker, Lauryn A.; Arulselvan, Abinaya; Cohen, A. Sarah; Lambert, Michele P.; Despotovic, Jenny M. (2020). “Racial variation in ITP prevalence and chronic disease phenotype suggests biological differences”. Blood. 136 (5): 640–643. doi:10.1182/blood.2020004888. ISSN 0006-4971.

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