Incidentaloma classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D [2]

Overview

Adrenal incidentaloma may be classified as functioning (secreting) or nonfunctioning incidentaloma. Adrenal incidentaloma may also be classified by the nature into benign masses or malignant masses.

Classification

Adrenal incidentaloma may be classified by its function into:^[1]^[2]^[3]^[4]^[5]

Functioning (hormone secreting):
- Adenomas and carcinomas can secrete any type of adrenal hormone.
- Most of the adrenal incientalomas secrete excess cortisol with minimal signs of Cushing’s syndrome that may not be noticed.
- Pheochromocytomas secrete catecholamines.
- Aldosterone secreting masses may present with hypertension and hypokalemia.
Nonfunctioning (nonhormonal secreting):

Adrenal incidentaloma may be classified on the basis of the nature, into:

References

↑ Grumbach MM, Biller BM, Braunstein GD, Campbell KK, Carney JA, Godley PA; et al. (2003). “Management of the clinically inapparent adrenal mass (“incidentaloma”)”. Ann Intern Med. 138 (5): 424–9. PMID 12614096.
↑ Young WF (2000). “Management approaches to adrenal incidentalomas. A view from Rochester, Minnesota”. Endocrinol Metab Clin North Am. 29 (1): 159–85, x. PMID 10732270.
↑ Sidhu S, Sywak M, Robinson B, Delbridge L (2004). “Adrenocortical cancer: recent clinical and molecular advances”. Curr Opin Oncol. 16 (1): 13–8. PMID 14685087.
↑ Lacroix A, Feelders RA, Stratakis CA, Nieman LK (2015). “Cushing’s syndrome”. Lancet. 386 (9996): 913–27. doi:10.1016/S0140-6736(14)61375-1. PMID 26004339.
↑ Raff H, Carroll T (2015). “Cushing’s syndrome: from physiological principles to diagnosis and clinical care”. J Physiol. 593 (3): 493–506. doi:10.1113/jphysiol.2014.282871. PMC 4324701. PMID 25480800.

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[pmid12614096-1] Grumbach MM, Biller BM, Braunstein GD, Campbell KK, Carney JA, Godley PA; et al. (2003). “Management of the clinically inapparent adrenal mass (“incidentaloma”)”. Ann Intern Med. 138 (5): 424–9. PMID 12614096.

[pmid10732270-2] Young WF (2000). “Management approaches to adrenal incidentalomas. A view from Rochester, Minnesota”. Endocrinol Metab Clin North Am. 29 (1): 159–85, x. PMID 10732270.

[pmid14685087-3] Sidhu S, Sywak M, Robinson B, Delbridge L (2004). “Adrenocortical cancer: recent clinical and molecular advances”. Curr Opin Oncol. 16 (1): 13–8. PMID 14685087.

[pmid26004339-4] Lacroix A, Feelders RA, Stratakis CA, Nieman LK (2015). “Cushing’s syndrome”. Lancet. 386 (9996): 913–27. doi:10.1016/S0140-6736(14)61375-1. PMID 26004339.

[pmid25480800-5] Raff H, Carroll T (2015). “Cushing’s syndrome: from physiological principles to diagnosis and clinical care”. J Physiol. 593 (3): 493–506. doi:10.1113/jphysiol.2014.282871. PMC 4324701. PMID 25480800.

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Incidentaloma classification

Overview

Classification

References

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