Health Dictionary
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Indoprofen
Introduction
Indoprofen is a non-steroidal anti-inflammatory drug. It was withdrawn worldwide in the 1980s after postmarketing reports of severe gastrointestinal bleeding.[1]
A 2004 study using high-throughput screening found indoprofen to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for spinal muscular atrophies.[1][2]
References
- ↑ 1.0 1.1 Frazin, Natalie (March 9 2005). “Pain Reliever May Provide Clues for Treating Spinal Muscular Atrophy”. United States National Institute of Neurological Disorders and Stroke. Retrieved 2007-10-06. Check date values in:
|date=(help) - ↑ Lunn MR, Root DE, Martino AM; et al. (2004). “Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism”. Chem Biol. 11 (11): 1489–93. doi:10.1016/j.chembiol.2004.08.024. PMID 15555999.