Indoprofen

Indoprofen is a non-steroidal anti-inflammatory drug. It was withdrawn worldwide in the 1980s after postmarketing reports of severe gastrointestinal bleeding.^[1]

A 2004 study using high-throughput screening found indoprofen to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for spinal muscular atrophies.^[1]^[2]

References

↑ ^1.0 ^1.1 Frazin, Natalie (March 9 2005). “Pain Reliever May Provide Clues for Treating Spinal Muscular Atrophy”. United States National Institute of Neurological Disorders and Stroke. Retrieved 2007-10-06. Check date values in: |date= (help)
↑ Lunn MR, Root DE, Martino AM; et al. (2004). “Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism”. Chem Biol. 11 (11): 1489–93. doi:10.1016/j.chembiol.2004.08.024. PMID 15555999.