Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Inosine-5'-monophosphate dehydrogenase
Introduction
Inosine-5′-monophosphate dehydrogenase (IMPDH) is an enzyme which salvages purines to make guanine in the human pathogen Cryptosporidium parvum. The C. parvum enzyme IMPDH differs enough from human IMPDH to serve as a drug target. [Chem. Biol. 15, 70 (2008)]
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]