Interferon alfacon-1 contraindications

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sophia Saad, Associate Editor – WikiDoc [2]

Contraindications

INFERGEN is contraindicated in patients with

hepatic decompensation (Child-Pugh score >6 [class B and C])
autoimmune hepatitis
known hypersensitivity reactions such as urticaria, angioedema, bronchoconstriction, anaphylaxis to interferon alphas or to any component of the product

Additionally, ribavirin is contraindicated in:

women who are pregnant
men whose female partners are pregnant
patients with hemoglobinopathies (e.g., thalassemia major, sickle-cell anemia)
patients with hypersensitivity to ribavirin or any other component of the product
patients with creatinine clearance <50 mL/min.^[1]

References

Adapted from the FDA Package Insert.

Contraindications