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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Intraductal papilloma

Introduction

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Overview

Overview

Intraductal papillomas of the breast are relatively common benign lesions with an incidence of approximately 2-3% in humans.[1] They are the most common cause of bloody nipple discharge in women age 20-40 and generally do not show up on mammography due to their small size, so the next step in treatment would be a galactogram to guide the subsequent biopsy.The masses are often too small to be palpated or felt. A galactogram is therefore necessary to rule out the lesion. Excision is sometimes performed as the method of treatment.[2]

Additional Images

Additional Images

  • Histopathology of intraductal papilloma of the breast by excisional biopsy. Hematoxylin and eosin stain.
    Histopathology of intraductal papilloma of the breast by excisional biopsy. Hematoxylin and eosin stain.
  • Histopathology of intraductal papilloma of the breast by excisional biopsy. Immunostaining for alpha-smooth muscle actin.
    Histopathology of intraductal papilloma of the breast by excisional biopsy. Immunostaining for alpha-smooth muscle actin.
References

References

  1. ↑ Cilotti A, Bagnolesi P, Napoli V, Lencioni R, Bartolozzi C (1991). “[Solitary intraductal papilloma of the breast. An echographic study of 12 cases]”. La Radiologia Medica (in Italian). 82 (5): 617–20. PMID 1780459. Unknown parameter |month= ignored (help)
  2. ↑ Ahmadiyeh N, Stoleru MA, Raza S, Lester SC, Golshan M (2009). “Management of intraductal papillomas of the breast: an analysis of 129 cases and their outcome”. Ann. Surg. Oncol. 16 (8): 2264–9. doi:10.1245/s10434-009-0534-1. PMID 19484312. Unknown parameter |month= ignored (help)

Template:Epithelial neoplasms Template:Breast neoplasia

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]