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Iodine deficiency overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

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Overview

Overview

Iodine is an essential trace element; the thyroid hormones thyroxine and triiodotyronine contain iodine. In areas where there is little iodine in the diet—typically remote inland areas where no marine foods are eaten—iodine deficiency gives rise to goiter (so-called endemic goitre), as well as cretinism, which results in developmental delays and other health problems

In some such areas, this is now combatted by the addition of small amounts of iodine to table salt in form of sodium iodide, potassium iodide, potassium iodate—this product is known as iodized salt. Iodine compounds have also been added to other foodstuffs, such as flour, in areas of deficiency.

Historical Perspective

Historical Perspective

Classification

Classification

Pathophysiology

Pathophysiology

Causes

Causes

Differentiating Iodine Deficiency from Other Diseases

Differentiating Iodine Deficiency from Other Diseases

Epidemiology and Demographics

Epidemiology and Demographics

Risk Factors

Risk Factors

Screening

Screening

Natural History, Complications, and Prognosis

Natural History, Complications, and Prognosis

Diagnosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Treatment

Medical Therapy

Surgery

Prevention

References

References

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