
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Isoindole
Introduction
Isoindole in heterocyclic chemistry is a benzo fused pyrrole.[1] The compound is an isomer of indole and its reduced form is an isoindoline.
In solution the non-aromatic tautomer is predominant:
and therefore the compound resembles a pyrrole more than a simple imine. Isoindoles are building blocks for phthalocyanines which are relevant as dyes
Isoindole-1,3-diones
Isoindole-1,3-diones
The commercially important phthalimide is an isoindole-1,3-dione with two carbonyl groups attached to the heterocyclic ring. Thalidomide is an infamous drug based on this framework.
