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Isoindole

Isoindole
Isoindole

Isoindole in heterocyclic chemistry is a benzo fused pyrrole.[1] The compound is an isomer of indole and its reduced form is an isoindoline.

In solution the non-aromatic tautomer is predominant:

Isoindole tautomerism


and therefore the compound resembles a pyrrole more than a simple imine. Isoindoles are building blocks for phthalocyanines which are relevant as dyes

Isoindole-1,3-diones

Isoindole-1,3-diones

The commercially important phthalimide is an isoindole-1,3-dione with two carbonyl groups attached to the heterocyclic ring. Thalidomide is an infamous drug based on this framework.


See also

See also

References

References

  1. Heterocyclic chemistry T.L. Gilchrist ISBN 0852014220

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