Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Isosthenuria
Introduction
Isosthenuria refers to the excretion of urine, the specific gravity (concentration) of which is neither greater (more concentrated) nor less (more dilute) than that of protein-free plasma. This is the hallmark of such disease states as chronic and acute renal failure in which the kidneys lack the ability to concentrate or dilute the urine and so the initial filtrate of the blood remains unchanged despite the need to conserve or excrete water based on the body’s hydration status.
Editor-In-Chief: Earl H. Rudolph, M.D.