
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
JUPITER
Introduction
Click here to download slides for JUPITER.
Overview
Overview
This most recent trial randomly assigned 17,802 healthy subjects with LDL < 130 mg/dL and high-sensitivity CRP > 2 g/L to Rosuvastatin 20 mg daily or placebo. A significant reduction in the composite and individual components of the primary end-point of myocardial infarction, stroke, arterial revascularization hospitalization for unstable angina or death from cardiovascular causes and all-cause mortality was noted and trial was stopped earlier at 1.9 years (maximum of 5 years)[1].
References
References
- ↑ Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ; et al. (2008). “Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein”. N Engl J Med. 359 (21): 2195–207. doi:10.1056/NEJMoa0807646. PMID 18997196. Review in: Evid Based Med. 2009 Apr;14(2):48 Review in: Ann Intern Med. 2009 Jan 20;150(2):JC1-4
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
