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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Japanese encephalitis natural history, complications and prognosis

Introduction

Overview

Overview

If left untreated, 50% of patients with Japanese encephalitis may progress to develop severe neurological deficits, such as deafness, hemiparesis, and aphasia. Common complications of Japanese encephalitis include seizures, coma, and spastic paralysis. Prognosis is generally poor. Approximately 20-30% of patients progress to mortality. Among patients who survive, approximately 50% suffer severe neurological, cognitive, or psychological deficits.

Natural History

Natural History

If left untreated, 50% of patients with Japanese encephalitis may progress to develop severe neurological deficits, such as deafness, hemiparesis, and aphasia.[1][2]

Complications

Complications

Common complications of Japanese encephalitis include:[3][4]

Prognosis

Prognosis

Prognosis is generally poor. Approximately 20-30% of patients progress to mortality. Among patients who survive, approximately 50% suffer severe neurological, cognitive, or psychological deficits.[1][3]

References

References

  1. ↑ 1.0 1.1 Khandaker G, Zurynski Y, Buttery J, Marshall H, Richmond PC, Dale RC; et al. (2012). “Neurologic complications of influenza A(H1N1)pdm09: surveillance in 6 pediatric hospitals”. Neurology. 79 (14): 1474–81. doi:10.1212/WNL.0b013e31826d5ea7. PMC 4098823. PMID 22993280.
  2. ↑ M.D. JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, Expert Consult Premium Edition. Saunders; 2014.
  3. ↑ 3.0 3.1 Japanese encephalitis – Fact sheet No 386. World Health Organization (WHO) (2015) http://www.who.int/mediacentre/factsheets/fs386/en/ Accessed on April 12, 2016
  4. ↑ Japanese Encephalitis, Clinical and Laboratory Evaluation. Centers for Disease Control and Prevention (2015). http://www.cdc.gov/japaneseencephalitis/healthcareproviders/healthcareproviders-clinlabeval.html Accessed on April 14, 2016.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anthony Gallo, B.S. [2]