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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Jaundice and pruritis

Introduction

The differential diagnosis for jaundice and pruritis are:

Disease History and clinical manifestations Diagnosis
Lab Findings Other blood tests Other diagnostic
AST ALT ALK BLR Indirect BLR Direct Viral serology
Type of jaundice Pruritis Family history
Common bile duct stone Cholestatic Jaundice + -/+ N N ↑ N ↑ – Dilated ducts on sono CT/ERCP
Hepatitis A cholestatic type + – N N ↑ N ↑ + HAV- AB Abdominal ultrasound
EBV / CMV hepatitis + – N N ↑ N ↑ + Positive serology PCR or ELISA
Primary biliary cirrhosis + -/+ N/↑ N/↑ ↑ N ↑ – AMA positive Liver biopsy
Primary sclerosing cholangitis + -/+ N/↑ N/↑ ↑ N ↑ – Beading on MRCP Liver biopsy
Autoimmune hepatitis Hepatocellular Jaundice -/+ -/+ ↑ ↑ N ↑/N N – Anti-LKM antibody Liver biopsy