
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
KC6
Introduction
KC6 (“Keratoconus gene 6”) is a novel gene located on chromosome 18 at p12.3. It was discovered by Rabinowitz et al. (2005)[1] in a study whose aims were finding genes expressed in human cornea and increasing the knowledge of molecular changes in keratoconus. It lies adjacent to the PIK3C3 gene, but is apparently non-protein coding. Its function is unknown so far and the only study available is that of its discovery. Authors suggest that the gene may be cornea-specific in its expression.
References
References
- ↑ Rabinowitz YS, Dong L, Wistow G (April 2005). “Gene expression profile studies of human keratoconus cornea for NEIBank: a novel cornea-expressed gene and the absence of transcripts for aquaporin 5” (PDF). Invest. Ophthalmol. Vis. Sci. 46 (4): 1239–46. doi:10.1167/iovs.04-1148. PMID 15790884.
