Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
KDM8
Introduction
Lysine demethylase 8 is a protein that in humans is encoded by the KDM8 gene. [1]
Function
Function
This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.
Further reading
Further reading
- Suzuki T, Minehata K, Akagi K, Jenkins NA, Copeland NG (2006). “Tumor suppressor gene identification using retroviral insertional mutagenesis in Blm-deficient mice”. EMBO J. 25 (14): 3422–31. doi:10.1038/sj.emboj.7601215. PMC 1523184. PMID 16858412.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.